Öfke kontrolü erken çocukluk döneminde başlar ve beyin ön bölgesinin bir işlevidir. Çocuklara karşı olan yanlış tutumlar, kötü çocukluk çağı yaşantıları ve travmaları çocuklarda öfke kontrolünü bozar. Öfke Kontrol Bozukluğu yaşayan bireylerde serotonin adı verilen mutluluk hormonunun çalışmasında da bir sorun olduğu bilinmektedir.
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